TWiV 843: COVID-19 clinical update #93 with Dr. Daniel Griffin

In COVID-19 clinical update #93, Dr. Griffin summarizes Omicron fitness, S-gene target failure, monoclonal efficacy against Omicron, vaccination, monoclonals, and disease in children, persistence of memory B cells in the elderly, infection and vaccine induced immunity, protection against severe illness and death by a third mRNA vaccine dose, high flow oxygen versus intubation, and therapeutic anticoagulation. Hosts: Daniel Griffin and Vincent Racaniello Subscribe (free): iTunes , Google Podcasts , RSS , email Become a patron of TWiV! Links for this episode Variant updates (CDC) List of diagnostic kits (Global Fund, pdf ) B1.1.529 escapes most antibodies (bioRxiv) mRNA vaccine third dose and Omicron (medRxiv) Outpatient strategies children and adolescents (AAP) Memory B cells persist in elderly (J Clin Invest) mRNA booster effect against Delta (Clin Inf Dis) Azithromycin meta-analysis (J Antimicrob Chemo) High-flow oxygen vs intubation (JAMA) Therapeutic anticoagulation (Ann Int Med) Africa cases surge (CIDRAP) Letters read on TWiV 843 Timestamps by Jolene . Thanks! Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to [email protected]