Immunity, GLP-1, Cholesterol & Gut Microbiome – TFP #012 | Mike Mutzel

In this episode of The Feldman Protocol, special guest Mike Mutzel explores groundbreaking research on the immune system, GLP-1, the gut microbiome and lean mass hyper-responders. They deep dive on the Lipid Energy Model, atherosclerosis mechanisms, immune system interactions, coronary artery imaging data, and conventional cardiovascular risk paradigms in metabolic health.

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⏱ Chapters

3:01 – Introduction and Mike's background

9:14 – Medicine and nutrition evolution

17:44 – Mindful eating and GLP-1 connections

25:00 – Dave's cholesterol discovery story

31:42 – Understanding lipid trafficking physics

40:18 – Endothelial dysfunction and inflammation

49:00 – LDL oxidation and modification theories

58:23 – Atherosclerosis as immune response

1:05:47 – Blood viscosity and cardiovascular risk

1:15:19 – Self-censorship in scientific discourse

1:25:33 – Continual exposure hypothesis debate

1:32:19 – Own Your Labs citizen science project

1:40:58 – Cholesterol paradox in aging populations

1:50:33 – Metabolic health vs inflammation

2:00:12 – Radiation concerns with CT angiograms

2:08:56 – Triglycerides and ketogenic metabolism

2:18:47 – Study results and mainstream response

2:22:41 – Final thoughts and future research

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