42. ASCO 2023 - Gastroesophageal, Pancreatic and Hepatobiliary update

ASCO 23 (American Society of Clinical Oncology) Annual Meeting in Chicago showcased a plethora of cutting-edge trials and research. Upper gastrointestinal cancers such as gastric, pancreatic and hepatobiliary are usually relegated to the backstage, but this year, several exciting and potentially practice-changing studies (not without their limitations).

We explore a new PD-1Toripalimab in gastric and gastroesophageal cancer, liposomal irinotecan in NALIRIFOX versus gemcitabine/abraxane in metastatic pancreatic cancer, neoadjuvant FOLFIRINOX in pancreatic cancer and the new HER2 kid on the block zanidatamab, a bispecific monoclonal antibody.

Stay tuned for daily ASCO updates from the OFTIM team, Michael and Josh.

Studies:

Toripalimab + SOX study: https://meetings.asco.org/abstracts-presentations/219777

NAPOLI-3 study: https://meetings.asco.org/abstracts-presentations/222090

NORPACT-1 study: https://meetings.asco.org/abstracts-presentations/219426

HORIZON-BTC-01 study: https://meetings.asco.org/abstracts-presentations/219904

Special Mention (not included in the episode)

DIPLOMA Study: https://meetings.asco.org/abstracts-presentations/218312

Lauren Classification: https://open.acast.com/shows/62d20dbcffef490011c8df4b/episodes

Many thanks to Merck for supporting this episode. Merck provided virtual access to ASCO 2023 but did not review or approve any part of OftiM's coverage of ASCO.

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