18. Metastatic Colorectal Cancer

In this episode, Josh and Mikey travel back millions of years to a time when dinosaurs roamed the Earth, as recent research has demonstrated, unmolested by cancer. Then they come crashing back to the present to discuss this week's topic, metastatic colorectal cancer. Will they discover secrets hidden across the aeons? Was the secret to cancer treatment hidden in the bones of our scaled precursors? No, of course not. But there will be a lot of information on the improving treatment of colorectal cancer, which has not taken millions of years to advance. Oh, and Michael does a passable Richard Attenborough.

Links to studies discussed in this episode (subscription may be required):

FIRE-3: https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(14)70330-4/fulltext

KEYNOTE 177: https://www.nejm.org/doi/full/10.1056/NEJMoa2017699

BEACON: https://www.nejm.org/doi/full/10.1056/NEJMoa1908075

Epidemiological Study of Tumours in Dinosaurs: https://link.springer.com/article/10.1007/s00114-003-0473-9

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Art courtesy of Taryn Silver

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