358: Gut Microbes and ALS
TWiM explains the connection between inflammation caused by microbial glycogen in the gut and amyotrophic lateral sclerosis, and how disruption of cysteine metabolism leads to synthetic lethality and in vivo fitness impairment in Acinetobacter baumannii.
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Links for this episode:
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Myeloid cell gene prevents inflammatory response to microbial glycogen (Cell Rep)
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Cysteine metabolism and fitness impairment in Acinetobacter baumannii (mBio)
Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.
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