TWiV 879: Indolent, resistant, and losing our TMPRSS

TWiV reviews the emergence of remdesivir-resistant SARS-CoV-2 during treatment of a persistently infected immunocompromised patient, and how altered TMPRSS2 utilization by the Omicron variant influences infectivity and fusion. Hosts: Vincent Racaniello , Alan Dove , Rich Condit , Kathy Spindler , and Brianne Barker Subscribe (free): Apple Podcasts , Google Podcasts , RSS , email Become a patron of TWiV! Links for this episode ASV 2022 Emergence of remdesivir resistance (Nature Comm) How to stall a copy machine ( TWiV 819 ) Omicron altered TMPRSS2 usage (Nature) Timestamps by Jolene . Thanks! Weekly Picks Brianne – NSURP 2022 Kathy – Virology Jobs Rich – 10 Steps from Seed to Cup ( Graphic ) Alan – Fathoms: The World in The Whale , by Rebecca Giggs Vincent – Worldwaterday.org Listener Picks Jeremy – Archaeology of Light Intro music is by Ronald Jenkees Send your virology questions and comments to [email protected]