August 21 2026 This Week in Cardiology

Mechanical CPR devices, the dangers of AF performance measures, two scholarly articles on CLOSURE and CHAMPION, and a little ESC preview are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Mechanical Compression Devices for OHCA · Mechanical CPR Device Use Cardiac Arrest Survival https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.126.079272 · PARAMEDIC Trial https://www.thelancet.com/article/S0140-6736(14)61886-9/fulltext · CIRC Trial https://www.resuscitationjournal.com/article/S0300-9572(14)00128-2/fulltext · LINC trial https://jamanetwork.com/journals/jama/fullarticle/1774037 · Cochrane Review of Mechanical vs Manual Chest Compressions for Cardiac Arrest https://pmc.ncbi.nlm.nih.gov/articles/PMC6953326/ II ACC AF Performance Measures · 2026 AHA/ACC Clinical Performance for Patients With AF https://www.jacc.org/doi/10.1016/j.jacc.2026.05.032#sec-3 III Two Critical Appraisals of the recent LAAC trials · Reappraising CHAMPION-AF 10.1016/j.hrthm.2026.07.048 External Link · CHAMPION and CLOSURE: Reconciling Contrast Results https://doi.org/10.1093/eurheartj/ehag608 ESC Early Preview · CMR Guide trial https://pmc.ncbi.nlm.nih.gov/articles/PMC6931571/ · SINGLE AF Trial 10.1016/j.hroo.2025.12.008 External Link You may also like: The Bob Harrington Show with the Stephen and Suzanne Weiss Dean of Weill Cornell Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact [email protected]