Send us a text What if the hardest part of coming off an antidepressant isn’t the first cut, but the last milligrams? We sit down with Dr. Mark Horowitz—clinician, researcher, and someone who’s been through withdrawal himself—to unravel why standard advice fails, how the brain adapts to medication, and what a safer exit really looks like. Mark shares his first taper attempt after 13 years on Lexapro, a methodical plan that still crashed into panic, derealization, and hours of daily terror. That lived shock led him to survivingantidepressants.org, hyperbolic tapering, and ultimately co-authoring the Maudsley Deprescribing Guidelines and national guidance in the UK. We dig into the science behind tolerance and homeostasis, the neuroimaging that explains why tiny doses can have big effects, and the practical tools—liquid formulations and small percentage reductions—that let people step down without falling off a cliff. We also take on the evidence base. Most psychiatric drug trials are short, yet millions stay on meds for years. Stopping studies often confuse withdrawal with relapse, inflating claims for maintenance. Mark clarifies the dif Savorista Coffee is offering our listeners 25% off their premium craft decaf and half caf blends with bold flavors, ethically sourced beans, and natural decaffeination. Small-batch roasted for exceptional taste. E Use promo code GASLIT at checkout! https://savorista.com/discount/GASLIT Kenshō Cocktails by RSRV Collective are premium, non-alcoholic drinks crafted to deliver bold, sophisticated flavors inspired by classic cocktails—alcohol-free indulgence. Enjoy an exclusive discount 30% off using code GASLIT at checkout Good for anything purchased; it’s the best deal, and can’t be found anywhere else. https://rsrvcollective.com/discount/GASLIT 💊 Ready to Deprescribe Your Psych Meds? Psych meds have harmed us—and we’re not just survivors, we’re deeply educated in psychopharmacology, psychology, and nutrition. As hosts of The Gaslit Truth Podcast , we guide people safely off psychiatric medications with strategies grounded in science and brain health 🔥 You’ve been harmed. You’ve been dismissed. It’s time to take your brain back—with guidance from people who’ve been there and know their stuff. Support the show Are you tired of being gaslit and want to DEEP THROAT some more truth? We want to hear from you! Message us your gaslit stories at
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