The Substance

The Substance is a bloody, campy, fiercely feminist body horror film. Demi Moore plays a TV aerobics instructor who learns of a mysterious drug that causes another younger, entirely separate version of herself (Margaret Qualley) to splurt out of her back and assume her consciousness. The movie has earned Moore her first Oscar nomination, and she's the frontrunner in this year's best actress race. So we thought it would be the perfect time to revisit our conversation about the movie. In the run-up to the Oscars, Pop Culture Happy Hour is watching all 10 best picture nominees – and you're invited to join us! Sign up for the NPR Movie Club newsletter series and tell us what you thought of the movies you watched this week. Subscribe to Pop Culture Happy Hour Plus at plus.npr.org/happyhour Learn more about sponsor message choices: podcastchoices.com/adchoices NPR Privacy Policy