Ninja Nerds, Welcome to the Ninja Nerd Podcast with Zach and Rob! In this episode, we dive deep into Acute Leukemias , breaking down their pathophysiology, clinical presentation, and management. We explore the key differences between Acute Myeloid Leukemia (AML) and Acute Lymphoblastic Leukemia (ALL) , focusing on the genetic mutations, risk factors, and cellular mechanisms driving these malignancies. Our discussion includes high-yield diagnostic approaches such as peripheral blood smear, bone marrow biopsy, flow cytometry, and cytogenetic analysis . We also cover essential treatment strategies, including induction chemotherapy, targeted therapies, and hematopoietic stem cell transplantation (HSCT) , while highlighting critical complications like tumor lysis syndrome and leukostasis. This episode is packed with clinically relevant insights and board exam pearls—tune in and support us below! Support the show
