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NEW Season 1 Oct 19, 2026 · 1 hr 11 min

Which Businesses Will Survive AI? | Michael Dempsey

Will the AI labs eat everything or is tech just too sure of itself to tell what actually lasts? This week, Compound's Michael Dempsey explains why he invests against the herd in a market running on FOMO. We explore which SaaS companies survive AI, why sentiment has turned against tech, his case for a historic decade in bio, and why crypto venture went quiet while onchain assets got interesting. Enjoy! TIMESTAMPS: 00:00 Intro 01:29 How Do You Invest Without FOMO? 08:30 Is The AI Boom Built To Last? 12:32 Will AI Labs Eat Every Startup? 17:19 Ads (Fidelity Crypto) 17:52 Which Software Companies Survive AI? 24:35 Why Is Tech Losing Public Trust? 33:56 Ads (Fidelity Crypto) 34:35 Gambling, Inequality, And Financial Nihilism 40:03 Has Tech Lost Its Soul? 43:54 How Compound Finds Its Next Bets 55:36 Can AI Transform Biotech? 01:03:39 Why Still Invest In Crypto? 01:08:04 Which Crypto Companies Could Go Public? FOLLOW GUEST › Michael – https://x.com/mhdempsey › Compound – https://www.compound.vc/ FOLLOW THE SHOW › Empire – https://x.com/theempirepod › Jason – https://x.com/jasonyanowitz › Telegram – https://t.me/+CaCYvTOB4Eg1OWJh › Blockworks – https://x.com/Blockworks SPONSORS › Fidelity Crypto was built in-house with over a dozen years of crypto experience. So you can trade crypto and stocks in one place at Fidelity, backed by industry-leading security. Fidelity Crypto. We're here to help you feel good about investing in crypto. Crypto is offered by Fidelity Digital Assets, NA, is not insured by FDIC or SIPC and includes risk of significant loss. Securities offered by Fidelity Brokerage Services,LLC. Member NYSE, SIPC. http://fidelity.com/crypto EVENTS › Join us at Digital Asset Summit London Nov 10-11 https://blockworks.com/events RESOURCES › Learn more about Blockworks Agentic Detection: https://blockworks.com/insights/introducing-agentic-detection-asset-monitoring-built-for-the-ai-era › Start building with the Blockworks Unified API https://blockworks.com/insights/introducing-the-blockworks-unified-api DISCLAIMER Nothing said on Empire is a recommendation to buy or sell securities or tokens. This podcast is for informational purposes only. Any views expressed are opinions, not financial advice. Hosts and guests may hold positions in the companies, funds, or projects discussed.

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