Ovarian Syndrome Linked to Fourfold Higher Heart Disease Risk
- Women with polyendocrine metabolic ovarian syndrome (PMOS), the condition formerly called polycystic ovary syndrome (PCOS), showed a more than fourfold higher rate of artery disease in a large U.S. study based on more than two decades of health insurance records
- The analysis included more than 413,000 women with PMOS and over 2 million women without the condition, with an average age of just over 31, showing that cardiovascular risk can emerge during the reproductive years
- High blood pressure, high cholesterol, Type 2 diabetes, and obesity explained only about 36% of the association, suggesting that PMOS itself may be an important cardiovascular risk-enhancing factor
- The recent change from PCOS to PMOS reflects a broader understanding of the condition as a multisystem endocrine and metabolic disorder rather than one centered on ovarian cysts
- Lifestyle strategies that address the metabolic patterns accompanying this diagnosis include eating adequate whole-food carbohydrates, cutting seed oils high in linoleic acid, regular walking and strength training, and limiting exposure to hormone-disrupting chemicals
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