CRISPR. You may have heard about it in the news. It's arguably the biggest discovery of the 21st century, and could possibly be a cure for some of the genetic disorders that have plagued humans throughout our history. It was initially identified in the early 1990s and more recently it was discovered to be the immune system used by bacteria to fight off viral infections. Until recently there were no known mechanism for inhibiting the infections caused by these bacteria-infecting viruses. Dr. Joe Bondy-Denomy is a leader in the CRISPR field and discovered anti-CRISPRS, the system used by viruses to hide out from the bacterial CRISPR system. We talk with him about his discoveries in the field and the ethics of gene editing in humans.
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