Struggling with cognitive decline?
Cognitive decline is prolific; at least 25% of Americans over age 65 suffer from mild cognitive impairment, according to Scientific American.
Doctors like to tell their patients that there’s no cure for Dementia or Alzheimer’s, that you just need to suffer a slow decline of your mind for decades, and will be spending a small fortune on increasingly ineffective pharmaceutical drugs. Being diagnosed with a degenerative condition is not a death sentence; it can be overcome with an intentional and persistent biohacking strategy.
Smart Drugs
Piracetam -- This is probably the first thing I’d recommend because it falls at the intersection of being very safe, affordable, effective, and scientifically proven to improve the mind.
* It’s been used in a 20-year population study of cognitive decline in the elderly.
* Along with Ginkgo Biloba, it was identified as a promising pharmaceutical intervention in a 2018 German paper, Mitochondrial Function, Dynamics, and Permeability Transition: A Complex Love Triangle as A Possible Target for the Treatment of Brain Aging and Alzheimer’s Disease.
* A 2018 Taiwanese meta-analysis paper analyzed 235 selected studies [involving] 44,854 patients with dementia (mainly vascular dementia, Alzheimer’s disease, and mild cognitive impairment). It identified Piracetam and Aniracetam as an effective intervention for dementia.
It imbues a cognitive edge both in the short and the long term; usually, it has an energizing effect that peps you up 40-60 minutes after dosing and improves verbal intelligence; it opens up your vocabulary. It’s a quintessential smart drug that imbues pleasantly intense focus. After several weeks or months of dosing, it has a more profound effect on your long-term memory -- it’s frequently reported that people remember obscure little things from their distant past. You’ll find yourself remembering the foreign language that you learned in high school as opposed to forgetting where you left your keys this morning.
While non-prescription and very safe, Piracetam is a hardcore drug that has an invasive effect on neurobiology. If you’re going to use it in the long term to upgrade your mind, you’ll want to combine it with a few cofactors in a specific protocol, the Piracetam Protocol, to maximize the cognitive bang for your buck.
There are other smart drugs in the Racetam family that are certainly interesting, and there are a lot of ways to use them, BUT Piracetam is probably the safest, cheapest, and most consistently effective for most people, so it’s what you should start with.
Phenylpiracetam -- This is a supercharged version of Piracetam. There are three human clinical trials totaling nearly 500 human subjects that demonstrate a positive effect on cognitive decline.
Oxiracetam -- The anti-aging properties of this Racetam have been demonstrated in five human clinical trials.
Mitochondrial Dysfunction
Cognitive decline has everything to do with Mitochondria, the little power plants of the cells. Dr. Lee Know explains in his book, The Future of Medicine
...compromised mitochondrial function is now seen as one of the leading causes of a wide range of seemingly unconnected degenerative diseases , and even the aging process itself .(1095-1096)
Alzheimer’s disease is the most common form of adult - onset dementia ; an eighty - year - old has about a 30 percent chance of developing Alzheimer’s . (1399-1400)
Based on the research I’ve done for this book, I would agree that the long-held beliefs about Alzheimer’s are falling apart and the most current research shows we need a greater focus on mitochondria in the prevention and treatment of the disease. (1409-1411)
Mitochondrial Nootropics
I have here the Mitochondrial Nootropics that deliver the best ROI and credible sources to order them from. Listed in descending order of the most effective and most economical, if you have a limited budget, get the ones near the top of the list...
* Glutathione (Source)
* Sulforaphane (Source)
* Methylene Blue (Source)
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