Dallas Cowboys face a must-win Monday Night Football showdown against the Arizona Cardinals, but Kyler Murray's late scratch changes everything. With backup Jacoby Brissett under center, can Dallas's struggling defense finally capitalize? Marcus Mosher and Landon McCool break down the critical defensive adjustments needed to contain tight end Trey McBride and Arizona's passing attack. The discussion covers offensive coordinator Klayton Adams' return to face his former team, attacking Jonathan Gannon's quarters-heavy defense, and whether CeeDee Lamb's health will determine the outcome. Key strategic questions emerge: Should the Cowboys blitz aggressively or play conservatively? Can Dak Prescott exploit Arizona's young secondary with quick-rhythm passing? The hosts deliver game predictions while emphasizing the brutal reality—at 3-4-1, with Philadelphia, Kansas City, Detroit, and Minnesota looming, this game could define Dallas's entire season. Discover why this matchup represents the Cowboys' last realistic chance at playoff contention and what tactical adjustments could turn their season around. Support Us By Supporting Our Sponsors! BILT Turn your rent into rewards and start earning points around your neighborhood by going to https://joinbilt.com/lockedonnfl . Supply House Join the free TradeMaster program today and score serious perks like priority shipping, lower prices, and a dedicated support line. Visit https://SupplyHouse.com to sign up for free and use promo code SHNFL5 for 5% off your first order. Peloton Let yourself run, lift, flex, and push forward. Explore the new Peloton Cross Training Tread+ today at https://www.onepeloton.com . PrizePicks Download the PrizePicks app today and use code LOCKEDONNFL to get $50 in lineups after you play your first $5 lineup. Click Here: https://prizepicks.onelink.me/LME0/LOCKEDONNFL Gametime Download the Gametime app, create an account, and use code LOCKEDONNFL for $20 off your first purchase. Terms apply. Download Gametime today. What time is it? Gametime. FanDuel Right now, new customers can bet just FIVE dollars and if your bet wins—you’ll get THREE HUNDRED dollars in bonus bets to use across the app. FANDUEL DISCLAIMER : 21+ in select states. First online real money wager only. Bonus issued as nonwithdrawable free bets that expires in 14 days. Restrictions apply. See terms at sportsbook.fanduel.com. Gambling Problem? Call 1-800-GAMBLER or visit FanDuel.com/RG (CO, IA, MD, MI, NJ, PA, IL, VA, WV), 1-800-NEXT-STEP or text NEXTSTEP to 53342 (AZ), 1-888-789-7777 or visit ccpg.org/chat (CT), 1-800-9-WITH-IT (IN), 1-800-522-4700 (WY, KS) or visit ksgamblinghelp.com (KS), 1-877-770-STOP (LA), 1-877-8-HOPENY or text HOPENY (467369) (NY), TN REDLINE 1-800-889-9789 (TN) Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
