Podcasts//The Readout Loud
The Readout Loud

The Readout Loud

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STAT’s weekly biotech podcast, breaking down the latest news, digging deep into industry goings-on, and giving you a preview of the week to come.
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Épisodes25
381: The future of American science and a dispatch from ASH

381: The future of American science and a dispatch from ASH

Dec 11, 2025·

How did Terns Pharmaceuticals and its “hodgepodge” pipeline grab attention at the American Society of Hematology conference? Is Eli Lilly’s new drug making people lose too much weight? And what, exactly, is the Trump...

380: A new top drug regulator and the future of psychedelics

380: A new top drug regulator and the future of psychedelics

Dec 4, 2025·

On this week’s episode of "The Readout Loud": a look at an emerging class of psychedelic drugs that may treat depression, anxiety, and other psychiatric conditions without the hallucinogenic “trip.” Plus, a dash through...

379: How Mark Cuban plans to ‘f— up’ health care

379: How Mark Cuban plans to ‘f— up’ health care

Nov 20, 2025·

How much time does Mark Cuban spend thinking about health care? Why does he think TrumpRx, a direct drug purchasing platform that the Trump administration aims to launch, is “the most incredible program ever”? And what...

378: Merck's heart disease win and the FDA's new drug regulator

378: Merck's heart disease win and the FDA's new drug regulator

Nov 13, 2025·

What does Rick Pazdur's new role mean for the Food and Drug Administration? Has Merck solved the PCSK9 access issue? And how much credit can the president take for lowering GLP-1 drug prices? Dean Li, the head of R&D at...

377: Melodrama at the FDA and the Pfizer-Novo bidding war

377: Melodrama at the FDA and the Pfizer-Novo bidding war

Nov 6, 2025·

On a jam-packed show, your co-hosts, minus the vacationing Allison DeAngelis, chat with STAT’s D.C. correspondent Lizzy Lawrence about a slow-boiling feud between Vinay Prasad, the head of the FDA’s biologics and...

376: BridgeBio’s great week and Moderna’s unraveling

376: BridgeBio’s great week and Moderna’s unraveling

Oct 30, 2025·

Has BridgeBio’s business model worked? How are executives at Moderna dealing with the company’s slump? And who will the hosts dress up as for Halloween? We discuss all that on this week’s episode of the “The Readout...

375: Startups push the FDA and biotech booms in North Carolina

375: Startups push the FDA and biotech booms in North Carolina

Oct 23, 2025·

Can Trump take credit for North Carolina's booming biopharma industry? Which drugs could get a shortcut to the market? And who wore a tuxedo to the STAT Summit? We discuss all that and more in the latest episode of "The...

374: Veteran biotech executive Clive Meanwell on drug pricing and the obesity market

374: Veteran biotech executive Clive Meanwell on drug pricing and the obesity market

Oct 16, 2025·

On this week’s episode of “The Readout LOUD”: an interview with veteran biotech executive and company founder Clive Meanwell. Pfizer recently acquired one of Meanwell’s companies, the obesity drug developer Metsera, for...

373: Party in biotech land and AstraZeneca’s miscalculation

373: Party in biotech land and AstraZeneca’s miscalculation

Oct 9, 2025·

Where did former vaccine regulator Peter Marks find a new job? How did a math error cost AstraZeneca a rare disease candidate? And is biotech back? We discuss all that on this week’s episode of the “The Readout LOUD,”...

372: A pharma C-suite shakeup and Trump's deal with Pfizer

372: A pharma C-suite shakeup and Trump's deal with Pfizer

Oct 2, 2025·

How will we look back on Emma Walmsley's tenure as GSK's CEO? Why did one of the FDA's top drug officials call out an obscure lupus drug on LinkedIn? And will we ever stop talking about the pharma patent cliff?Adam is...

371: A gene therapy success in Huntington's and Trump's autism announcement

371: A gene therapy success in Huntington's and Trump's autism announcement

Sep 25, 2025·

We bring on UniQure CEO Matt Kapusta to discuss the company's announcement this week that its one-time treatment for Huntington’s disease significantly slowed down the neurological condition in a key study. We also chat...

370: Pharma sours on the U.K., plus biotech M&A's quiet roll

370: Pharma sours on the U.K., plus biotech M&A's quiet roll

Sep 18, 2025·

STAT's European correspondent Andrew Joseph calls in from the U.K. to the podcast to dissect why companies like Merck and GSK are putting their money elsewhere. We also discuss the Advisory Committee on Immunization...

369: Trump, Chinese biotech, and an industry career reshaped by illness

369: Trump, Chinese biotech, and an industry career reshaped by illness

Sep 11, 2025·

Listeners of this podcast probably know pharma consultant Mike Rea for his annual ranking of drug company R&D productivity. But this week, he penned a poignant personal essay explaining how some medical setbacks have...

368: New stakes in the vaccine dispute and a boost for biotech

368: New stakes in the vaccine dispute and a boost for biotech

Sep 4, 2025·

Labor Day is in the rearview mirror, and that means Adam, Elaine, and Allison are all back to work. They take the pulse of the biotech market and discuss forthcoming data readouts at two sleep and lung disorder...

367: The ouster of CDC's director, biotech venture firm rankings

367: The ouster of CDC's director, biotech venture firm rankings

Aug 28, 2025·

We bring on Washington correspondent Chelsea Cirruzzo to explain the ouster of CDC Cirector Susan Monarez and the resignations of other top officials. We also chat about STAT's annual VC rankings report, as well as...

366: Viking’s obesity flop, ‘pharma to table’ drug sales

366: Viking’s obesity flop, ‘pharma to table’ drug sales

Aug 21, 2025·

On this week’s episode of “The Readout LOUD”: vikings. No, not the seafaring Norse people of the 10th century, or the Minnesota football team. The gang will discuss obesity drug developer Viking Therapeutics and the...

365: Vinay Prasad’s return, animal testing alternatives, and mRNA upended

365: Vinay Prasad’s return, animal testing alternatives, and mRNA upended

Aug 14, 2025·

We discuss the sudden return of Prasad and the mixed prospects for mRNA. Then, we invite STAT fellow Marissa Russo on to discuss the alternatives to animal testing, and why they’re the subject of hot debate among...

364: Closing a zombie biotech, and Lilly's disappointing obesity readout

364: Closing a zombie biotech, and Lilly's disappointing obesity readout

Aug 7, 2025·

We bring on Natalie Holles, who was the CEO of Third Harmonic Bio, which recently decided to dissolve and return cash to shareholders. She walks us through why the company has decided to do this and her advice for other...

363: What Vinay Prasad’s ouster means for biotech and the FDA

363: What Vinay Prasad’s ouster means for biotech and the FDA

Jul 31, 2025·

This week’s show is focused on a single topic — the ouster of Food and Drug Administration official Vinay Prasad from his job running the agency’s biologics division. This surprising development came after a series of...

362: A mother’s perspective on Sarepta’s gene therapy halt

362: A mother’s perspective on Sarepta’s gene therapy halt

Jul 24, 2025·

We bring on a mother whose 7-year-old has Duchenne muscular dystrophy, and hear her thoughts on Sarepta’s decision to pull its treatment Elevidys from the market, following a request from the Food and Drug...

361: Inside an FDA drug rejection, and layoffs at Sarepta

361: Inside an FDA drug rejection, and layoffs at Sarepta

Jul 17, 2025·

Just how many employees is Sarepta Therapeutics laying off? And why did the Food and Drug Administration reject Ultragenyx’s rare disease drug over manufacturing qualms? Ultragenyx CEO Emil Kakkis joins us to discuss...

360: NIH grant cuts, FDA transparency questions and biotech M&A

360: NIH grant cuts, FDA transparency questions and biotech M&A

Jul 10, 2025·

On this week’s episode of the Readout LOUD: A closer look at the NIH’s grant-cutting legal playbook, a not-so-transparent transparency push by the FDA commissioner, and another big biotech acquisition. Our colleague...

359: Vaccine policy frays, CDC nominee in the hot seat, & obesity drug side effects

359: Vaccine policy frays, CDC nominee in the hot seat, & obesity drug side effects

Jun 26, 2025·

We invite STAT’s senior writer for infectious diseases, Helen Branswell, and Washington correspondent Chelsea Cirruzzo on to the podcast to discuss the latest news at the CDC. The agency is in the spotlight once again...

358: FDA's gene therapy turmoil, and an alternative model for funding research

358: FDA's gene therapy turmoil, and an alternative model for funding research

Jun 19, 2025·

We discuss the tragic news that a second teenage boy with Duchenne muscular dystrophy died after taking Sarepta Therapeutics' gene therapy, raising renewed questions about the FDA's standards for approving drugs.We look...

357: The upheaval of CDC's vaccine panel, and drug pricing confusion

357: The upheaval of CDC's vaccine panel, and drug pricing confusion

Jun 12, 2025·

First, we chat about how pharma companies still don’t have much clarity on Trump’s most-favored nation drug pricing policy, biotech’s next big takeout target, and more. Then we bring on Kathryn Edwards, a vaccine expert...

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