Podcasts//MeSsy with Christina Applegate & Jamie Lynn Sigler
MeSsy with Christina Applegate & Jamie Lynn Sigler

MeSsy with Christina Applegate & Jamie Lynn Sigler

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On this podcast, Christina Applegate and Jamie Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.
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Episódios25
Are You Mad At Me? with Meg Josephson

Are You Mad At Me? with Meg Josephson

Dec 16, 2025·

This week, Christina and Jamie are joined by Meg Josephson, author of “Are You Mad at Me?: How to Stop Focusing on What Others Think and Start Living for You.” They discuss the fawn response, how to start healing, the...

Montel Williams

Montel Williams

Dec 9, 2025·

This week Christina and Jamie are joined by Montel Williams. They discuss his experience living with MS, bedside manner, why being ill doesn’t make you weak, and more. Executive Producers: Christina Applegate, Jamie...

We're All Crushing It

We're All Crushing It

Dec 2, 2025·

This week, Christina and Jamie read listener emails and discuss perspective, not stuffing your feelings down, journaling, and much more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick...

How to Feel Safe in Your Body with Deb Dana (Re-Release)

How to Feel Safe in Your Body with Deb Dana (Re-Release)

Nov 25, 2025·

This week, Christina and Jamie are revisiting their conversation with Deb Dana, LCSW, a clinician and speaker specializing in complex trauma. They discuss how to understand our nervous systems, polyvagal theory, how to...

You Don’t Deserve to Feel Guilt

You Don’t Deserve to Feel Guilt

Nov 18, 2025·

This week, Christina and Jamie read listener emails and discuss big feelings, reality dating shows, guilt, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh...

Best of MeSsy: Edie Falco, Jean Smart, and Katey Sagal

Best of MeSsy: Edie Falco, Jean Smart, and Katey Sagal

Nov 11, 2025·

This week, we revisit conversations with three incredible guests: Edie Falco, Jean Smart, and Katey Sagal. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch...

Robert Iler

Robert Iler

Nov 4, 2025·

This week, Christina and Jamie are joined by Robert Iler, who starred on "The Sopranos" with Jamie. They discuss memories from their time on the show, his path to becoming sober, his friendship with Jamie, and much...

How Vulnerable Can I Be? with Craig Thomas

How Vulnerable Can I Be? with Craig Thomas

Oct 28, 2025·

This week Christina and Jamie are joined by Craig Thomas, an author and Co-Creator, Executive Producer and Writer of How I Met Your Mother. He shares his experience raising a son with Jacobsen Syndrome, discusses the...

We Don’t Move Past It, We Move With It

We Don’t Move Past It, We Move With It

Oct 21, 2025·

This week, Christina and Jamie read listener emails and discuss aging, being able to express emotions authentically, where to turn when you’re feeling stuck, and more. Executive Producers: Christina Applegate, Jamie...

Everybody’s Got Something

Everybody’s Got Something

Oct 14, 2025·

This week, Christina and Jamie read listener emails and discuss dynamic disability, not being alone in your struggles, the meaning we attach to things, and more. Executive Producers: Christina Applegate, Jamie Lynn...

It’s Okay to Be Yourself with Baylen Dupree

It’s Okay to Be Yourself with Baylen Dupree

Oct 7, 2025·

This week Christina and Jamie are joined by Baylen Dupree. She opens up about having Tourette syndrome, the importance of being yourself, why it's crucial to remember that everyone is struggling, and more. Executive...

Megan Mullally

Megan Mullally

Sep 30, 2025·

This week Christina and Jamie are joined by Megan Mullally. They discuss how her role as Karen on Will & Grace came to be, understanding family trauma, the comfort of TV, and more. Executive Producers: Christina...

Do What You Can When You Can

Do What You Can When You Can

Sep 23, 2025·

This week Christina and Jamie are joined by Christina’s friend, Cindy Locke. They share how they first connected online and discuss the impact of trauma, advice to people who are newly diagnosed, the importance of...

Fraser Olender

Fraser Olender

Sep 16, 2025·

This week, Christina and Jamie are joined by Fraser Olender from “Below Deck.” They discuss what his job as chief stew actually entails, his journey to find his true self, the escape of being busy, and much more...

We Are Not the Things That Happen to Us

We Are Not the Things That Happen to Us

Sep 9, 2025·

This week, Christina and Jamie read listener emails and discuss conditional friends, not identifying as the things that happen to us, staying honest, and more. Executive Producers: Christina Applegate, Jamie Lynn...

Change Your Brain, Change Your Pain with Dr. Daniel Amen

Change Your Brain, Change Your Pain with Dr. Daniel Amen

Sep 2, 2025·

This week, Christina and Jamie are joined by Dr. Daniel Amen, a physician, double board-certified psychiatrist, and award-winning researcher. They discuss why pain can also live in your brain, the doom loop and how to...

We Have to Pivot

We Have to Pivot

Aug 26, 2025·

This week, Christina and Jamie read listener emails and discuss their kids starting the new school year, the power of manifestation, accepting reality, and much more. Executive Producers: Christina Applegate, Jamie Lynn...

I Just Wanna Be Stoned

I Just Wanna Be Stoned

Aug 19, 2025·

This week, Christina and Jamie read listener emails and discuss hormones, housewives, acknowledging the struggle, and more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio...

Ed Helms

Ed Helms

Aug 12, 2025·

This week, Christina and Jamie are joined by Ed Helms. They discuss working together on "Vacation," his love of comedy, the importance of curiosity, and much more. Executive Producers: Christina Applegate, Jamie Lynn...

Live From the Hospital

Live From the Hospital

Aug 5, 2025·

This week, Christina joins Jamie live from the hospital in LA. They discuss what Christina’s going through, her recent trip abroad, their upcoming memoirs, the way the universe works, and much more. Executive Producers...

Jenny Mollen

Jenny Mollen

Jul 29, 2025·

This week, Christina and Jamie are joined by Jenny Mollen, a New York Times bestselling author and actor. They discuss the feeling of not being in control, the trials of parenting, and more. Executive Producers...

Easy on My Nervous System

Easy on My Nervous System

Jul 22, 2025·

This week, Christina and Jamie read listener emails and discuss wins and losses, shows that are easy on the nervous system, why people don't understand invisible diseases, and much more. Executive Producers: Christina...

Any Movement Counts with Doctor Gretchen

Any Movement Counts with Doctor Gretchen

Jul 15, 2025·

This week, Christina and Jamie are joined by Dr. Gretchen Hawley, an MS-certified specialist and physical therapist. They discuss what to do if you're feeling overwhelmed, the importance of staying consistent, why...

Life Is Like an Episode of Chopped

Life Is Like an Episode of Chopped

Jul 8, 2025·

This week, Christina and Jamie read listener emails and discuss body work, Christina’s new obsession, and much more. Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick Audio Engineer: Josh...

Clea Shearer

Clea Shearer

Jul 1, 2025·

This week, Christina and Jamie are joined by Clea Shearer. They discuss how The Home Edit came to be, Clea’s breast cancer diagnosis, and the importance of fighting for your health and trusting your gut. Executive...

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