"Risk management is really just planning for when things go wrong." In this final episode with Jimmy Sastra, PhD, co-founder and CEO of Monomer Bio, host Jon Chee explores how Jimmy redefines biotech leadership by treating fundraising as a strategic tool rather than a necessity. The conversation dives into building a company that combines scalable software with hands-on lab services, the importance of creativity and risk management in uncertain times, and Monomer’s bold vision for "autonomous science"—where AI and robotics revolutionize experimentation. Alongside deep biotech insights, Jimmy shares personal reflections on balancing entrepreneurship, family, and his immigrant journey while pushing the boundaries of automation in life sciences.