#25: Metformin For Long Covid

LongCovidMD.substack.com LongCovidMD.com In this episode of The Medicine Cabinet series, I explain how Metformin, a drug we often associate with diabetes, helps acute covid and may help Long Covid. Metformin is an old, relatively inexpensive medication that has many established off-label uses. I explain its mechanisms of action, who it might be right for, and I discuss the recently published COVID OUT research findings that supported metformin's use in acute infection. It reduces hospitalizations, death, and the development of Long Covid. What does that mean for those of us who already have Long Covid? I share my opinions. Research Links COVID OUT metformin dose used: 500mg on Day 1, 500mg twice daily on Days 2-5 and 500mg in the AM and 1,000mg in the PM on Days 6-14 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214027/ https://www.medrxiv.org/content/10.1101/2023.06.06.23290989v1 https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00299-2/fulltext#%20 https://academic.oup.com/cid/article/79/2/354/7660393?login=false https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10595158/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9111510/#:~:text=Recent%20evidence%20has%20shown%20that,has%20immunomodulatory%2C%20anti%E2%80%90inflammatory%2C CURE-ID Database https://cure.ncats.io/home Support the show Subscribe for free written summaries of each episode, resources, and more. LongCovidMD.substack.com/subscribe Support by donating at BuyMeACoffee