In this episode, Dr Rachel Grisham and Dr Kathleen Moore discuss newly approved treatments for low-grade serous ovarian cancer (LGSOC) and how recent research has transformed the therapeutic landscape for these patients, including: Molecular distinctions between low-grade and high-grade serous ovarian cancer that can guide therapy selection The recently approved targeted therapy combination regimen of avutometinib and defactinib for KRAS -mutant LGSOC (RAMP 201) Promising future directions for patients with LGSOC based on ongoing studies such as RAMP 301 and CHAMELEON Presenters: Rachel Grisham, MD Section Head of Ovarian Cancer Memorial Sloan Kettering Cancer Center Director Gynecologic Medical Oncology, MSKCC Westchester New York, New York Kathleen N. Moore, MD, MS, FASCO Deputy Director and Cancer Therapeutics Co-Lead Stephenson Cancer Center at the University of Oklahoma Professor Department of OB/Gyn ASCO BOD Oklahoma City, Oklahoma Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.